Yazar "Karabulut, Seda" için listeleme
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Administration of autologous platelet rich plasma and the impact on outcomes of assisted reproduction treatment in infertile women
Kutlu, Pelin; Karabulut, Seda; Korkmaz, Oya (IMR Press, 2021)Objective: There are diverse findings concerning the use of platelet-rich plasma (PRP) in assisted reproduction treatment (ART) cycles of infertile women with low ovarian reserve, ovarian failure or implantation failure ... -
Artificial oocyte activation with calcium ionophore for frozen sperm cycles
Karabulut, Seda; Aksünger, Özlem; Ata, Can; Sağıroğlu, Yusuf; Keskin, İlknur (Taylor and Francis Ltd., 2018)Fertilization problems are the major problems that may be faced in 30-55% of the patients during an intracytoplasmic sperm injection (ICSI) cycle. A successful oocyte activation depends on factors related to both sperm and ... -
Chronic unpredictable stress disturbs the blood-testis barrier affecting sperm parameters in mice
Kolbaşı, Bircan; Bülbül, Muhammet Volkan; Karabulut, Seda; Erdem Altun, Ceren; Çakıcı, Çağrı; Ülfer, Gözde; Müdok, Tangül; Keskin, İlknur (Elsevier Ltd, 2021)Research question: Does chronic stress affect the key proteins and sperm parameters of the blood & ndash;testis barrier (BTB)? Design: C57Bl/6 mice were divided into two groups: a non-treated control group and a chronic ... -
Comparison of machine learning classification techniques to predict implantation success in an IVF treatment cycle
Yiğit, Pakize; Bener, Abdulbari; Karabulut, Seda (Elsevier Science Ltd, 2022)Research question: Which machine learning model predicts the implantation outcome better in an IVF cycle? What is the importance of each variable in predicting the implantation outcome in an IVF cycle?Design: Retrospective ... -
Detailed morphological analysis of axolotl sperm
Keskin, İlknur; Gürsoy Gürgen, Duygu; Avinca, Didem; Özdemir, Ekrem Musa; Keskin, Suat Utku; Karabulut, Seda (Korean Society of Veterinary Science, 2021)The axolotl has extraordinary regeneration capacity compared to other vertebrates. This remarkable potential has been attributed to its life-long neoteny, characterized by the exhibition of embryonic characteristics at the ... -
Does a microfluidic chip for sperm sorting have a positive add-on effect on laboratory and clinical outcomes of intracytoplasmic sperm injection cycles? A sibling oocyte study
Yalçınkaya Kalyan, Ender; Can Çelik, Seren; Okan, Özlem; Akdeniz, Gülden; Karabulut, Seda; Çalışkan, Eray (Wiley, 2019)The most recent technologies for sperm sorting involve microfluidics. However, the most important question whether their use is of any advantage in terms of laboratory and clinical IVF/ICSI outcomes still remains controversy. ... -
Dondurulmuş ejekülat ve dondurulmuş testiküler spermin sonuçlarının intrasitoplazmik sperm enjeksiyonu (ICSI) parametrelerine etkisinin değerlendirilmesi
Karabulut, Seda; Korkmaz, Oya; Sağıroğlu, Yusuf; Keskin, İlknur (Avrasya Üroonkoloji Derneği, 2019)Amaç: Çalışmamızda, dondurulmuş ejekülat ve dondurulmuş testiküler spermin İntrasitoplaz - mik Sperm Enjeksiyonu (ICSI) sonuçları üzerine etkisinin araştırılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmamızda 11.10.2016- ... -
Effects o follicular fluid oxidative status on human mural granulosa cells, oocyte competency and ICSI parameters
Karabulut, Seda; Korkmaz, Oya; Kutlu, Pelin; Eren Gözel, Hilal; Keskin, İlknur (Elsevier, 2020)Purpose: The aim of the present study was to understand the molecular and genetic alterations involved in follicular fluid oxidative process by investigating human mural granulosa cells and to find possible biomarkers for ... -
Effects of density gradient sperm preparation on semen parameters and acrosomal status
Keskin, İlknur; Karabulut, Seda (Haydarpaşa Sample Training and Research Hospital, 2017)AbstractIntroduction: The aim of this study was to observe changes in sperm parameters after density gradient sperm preparation. These data will help to decide upon preparation technique and to predict the outcome of semen ... -
Effects of gallic acid on endometrial cancer cells in two and three dimensional cell culture models
Bülbül, Muhammet Volkan; Karabulut, Seda; Kalender, Mervenur; Keskin, İlknur (Asian Pacific Organization for Cancer Prevention, 2021)Background and Aim: Cell culture studies are an indispensable tools used to understand basic physiological, biophysical and biomolecular mechanisms. Although traditional two-dimensional (2D) cell culture models are more ... -
Effects of human sperm cryopreservation on apoptotic markers in normozoospermic and non-normozoospermic patients
Karabulut, Seda; Demiroğlu Zergeroğlu, Asuman; Yılmaz, Elif; Kutlu, Pelin; Keskin, Ilknur (Cambridge University Press, 2018)The negative effects of cryopreservation on sperm parameters are well documented but little information is known about molecular basis of the process. The aim of the present study was to investigate the possible effects ... -
Erkek infertilitesinde oksidatif stresin CAMP aracılı PKA yolağı proteinlerine ve ıcsı parametrelerine etkisinin araştırılması
Erdem Altun, Ceren (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2020)İnfertilite, çiftlerin en az 1 yıl süre ile korunmasız ve düzenli cinsel ilişkiye rağmen gebelik elde edilememesi olarak tanımlanmaktadır (DSÖ, 2010). Toplumun ~%15'inde görülen infertilite sorunu ile karşılaşan çiftler ... -
Erkek yaşı sperm parametrelerini etkiliyor mu? Türk popülasyonuna ait ilk seri
AMAÇ: Çalışmanın amacı, infertilite araştırma amacıyla elde edilmiş 1402 semen örneğinde, baba yaşı ile semen parametreleri (konsantrasyon, motilite, progresif motilite, morfoloji, akrozomal indeks, semen hacmi) arasındaki ... -
Factors related to follicular oxidative stress in intracytoplasmic sperm injection cycles and its effects on granulosa cells
Karabulut, Seda; Korkmaz, Oya; Kutlu, Pelin; Keskin, İlknur (Cambridge University Press, 2021)The aim of the present study was to investigate several common conditions that may potentially be correlated with follicular oxidative status during an intracytoplasmic sperm injection (ICSI) cycle and that include the ... -
Fresh versus frozen blastocyst transfer outcomes deriven from the same ICSI cycle in male factor infertility
Karabulut, Seda; Kutlu, Pelin; Korkmaz, Oya; Bülbül, Muhammet Volkan; Keskin, İlknur (IMR Press Limited, 2021)The aim of this study was to investigate the clinical outcomes of fresh and frozen-thawed blastocyst transfer deriven from the same ICSI cycle because of male infertility. 2372 couples undergoing a total of 5075 ICSI cycles ... -
A histopathological evaluation of ovarian hyperstimulation syndrome on reproductive and vital organs and the role of the VEGF-PKA pathway in a mouse model
Karabulut, Seda; Korkmaz, Oya; Erdem Altun, Ceren; Keskin, İlknur (Karger, 2021)Ovarian hyperstimulation syndrome (OHSS) is one of the most common and iatrogenic complications of in vitro fertilization therapy, which is an exaggerated response to excess hormones resulting in the development of a large ... -
Intracytoplasmic morphologically selected sperm injection, but for whom?
Karabulut, Seda; Aksünger, Özlem; Korkmaz, Oya; Eren Gözel, Hilal; Keskin, İlknur (Cambridge University Press, 2019)Intracytoplasmic sperm injection (ICSI) is performed in cases of infertility by injecting a motile and morphologically normal sperm cell under a routine ×400 magnification at which is hard to distinguish morphologically ... -
İleri baba yaşının sperm parametreleri, oksidatif stres, DNA fragmantasyonu, kromatin yapı ve mTOR ekspresyonuna etkilerinin incelenmesi
Atambay, Can (İstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, 2022)Çocuk sahibi olmanın getireceği maddi yükümlülükler nedeniyle günümüzde çoğu birey aile kurma ve çocuk sahibi olma planlarını daha ileri yaşa ertelemektedir. Bu çalışmada ileri baba yaşının sperm kalitesine ve fertiliteye ... -
Male infertility, azoozpermia and cryptozoospermia incidence among three infertility clinics in Turkey
Karabulut, Seda; Keskin, İlknur; Kutlu, Pelin; Delikara, Nuri; Atvar, Özhan; Öztürk, Metin İshak (AVES İbrahim Kara, 2018)Objective: Semen parameters are directly correlated with the infertility of the male. Incidence rates of male factor infertility, azoospermia and cryptozoospermia differ according to many factors such as geographic region, ... -
Psikofarmakolojik ilaçların sperm parametreleri, DNA'sı ve kromatin yapısına etkisinin araştırılması
Altıok, Uğurcan (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2021)İnfertilite, WHO tanımına göre çiftlerin 1 sene boyunca korumasız cinsel ilişkiye girmesine rağmen gebeliğin olmaması durumu olarak tanımlanmaktadır. Korunmayan çiftlerin %85'inde bir yıl içerisinde gebelik oluşurken ...